UDP-galactose

Description

UDP-Gal is a nucleotide sugar consisting of the nucleotide uridine 5'-diphosphate and a phosphate-bound monosaccharide, α-D-galactose. Nucleotide sugars are the activated forms of monosaccharides required for cellular metabolism and biosynthesis reactions. UDP-gal serves as a donor substrate for galactosyltransferases in the biosynthesis of galactose-containing glycans and oligosaccharides.

Appearance

Lyophilized white powder, hygroscopic

Purity

≥ 90 % (HPLC-UV). Product has not been tested for endotoxins

Solubility

Clear (> 50 mg/mL, H2O)

Storage

 -20°C

Special instructions

For research use only! Intended use for in vitro laboratory applications.

Toxicity & Safety

No health hazards have been reported so far. General rules for handling chemicals apply. Avoid skin and eye contact or ingestion. It is recommended to wear protective nitrile gloves and eye protection. Avoid aerosol formation.

Selected References

Rexer, T.;  Laaf, D.;  Gottschalk, J.;  Frohnmeyer, H.;  Rapp, E.; Elling, L., Enzymatic Synthesis of Glycans and Glycoconjugates. In Advances in Biochemical Engineering/Biotechnology, 2021; Vol. 175, pp 231-280.

Mahour, R.;  Lee, J. W.;  Grimpe, P.;  Boecker, S.;  Grote, V.;  Klamt, S.;  Seidel-Morgenstern, A.;  Rexer, T. F. T.; Reichl, U., Cell-Free Multi-Enzyme Synthesis and Purification of Uridine Diphosphate Galactose. ChemBioChem 2022, 23 (2).